CPT 95115 Allergy/Immunology

How Much Does Immunotherapy One Injection Cost?

Also known as: Immunotherapy one injection (CPT 95115)

Allergy immunotherapy injection (allergy shot) to gradually reduce your allergic reactions over time.

Immunotherapy One Injection (CPT 95115) costs $10 at Medicare rates.

Medicare (Facility)
$10
CMS PFS 2026 national rate

Patient Guide: Immunotherapy One Injection

What you need to know before your appointment

What to Expect

A nurse injects a small, gradually increasing dose of the allergens you are allergic to under the skin of your upper arm. You must wait 30 minutes after for monitoring.

How Long Does It Take?

5 minutes for the injection, 30 minutes for monitoring

Common Reasons Doctors Order This

Allergic rhinitis, allergic asthma, bee sting allergy, reducing allergy symptoms long-term

How to Prepare

Inform staff if you are feeling unwell or had a reaction to a previous shot. Wait the full 30 minutes for observation. Avoid vigorous exercise for 2 hours after.

Procedures Commonly Done Together

These procedures are frequently performed alongside Immunotherapy one injection

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How to Reduce Your Cost for Immunotherapy one injection

Practical tips that can save you hundreds or thousands of dollars

  • 1
    Ask about cash-pay discounts

    Many hospitals and clinics offer 20-40% discounts for self-pay patients. Always ask before scheduling.

  • 2
    Compare facility vs. office setting costs

    Some procedures cost significantly less in an office setting than a hospital. Ask your provider about options.

  • 3
    Shop around — costs vary significantly

    Costs can vary 2-3x between providers in the same city. Get quotes from multiple facilities.

Frequently Asked Questions

How much does Immunotherapy one injection cost?

The Medicare facility rate for Immunotherapy one injection is $10. Commercial insurance rates typically range from 150% to 250% of Medicare (varies by plan).

How much does Immunotherapy one injection cost without insurance?

Without insurance, the cost of Immunotherapy one injection can range from 150% of Medicare to 500% of Medicare depending on the facility. Many hospitals and clinics offer self-pay discounts of 20-40% off their chargemaster price. Always ask about cash pricing before your visit.

Does insurance cover Immunotherapy one injection?

Most commercial health insurance plans and Medicare cover Immunotherapy one injection when ordered by a physician for a medically necessary reason. Your out-of-pocket cost depends on your plan's deductible, copay/coinsurance structure, and whether you use an in-network provider. Check with your insurance company before scheduling to confirm coverage and get a cost estimate.

Why does the cost vary so much by location?

Medicare adjusts payments using Geographic Practice Cost Indices (GPCIs) that reflect local differences in physician work costs, practice expenses, and malpractice insurance. Manhattan, San Francisco, and other high-cost areas pay significantly more than rural regions. Commercial insurers follow similar geographic patterns.

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